POLYTAXEL
It Is the First-Line Anticancer Drug of Which the Toxicity Is Reduced
by Using Polymer Transfer Technologies.
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FIRST-LINE ANTICANCER DRUG
POLYTAXEL
Less Toxic Anticancer Drug Developed by Using Polymer Transfer Technologies
→ Polytaxel, which is called a ‘pain-free anticancer drug’, is a new material developed by encapsulating docetaxel, a typical type of chemotherapy, in advanced macromolecule-based drug delivery systems.The drug, which is about 10cm,are designed to be nano-sized so thatitis effectively delivered to organs into which drugs can’t be easily carried such as the pancreas. Additionally, docetaxel has been modified to overcome poor water-solubility so that the drug can be more effectively delivered to vital organs.
STRUCTURE OF POLYTAXEL
| Materials | Roles | Applications and Sales Activities |
|---|---|---|
| Docetaxel | Drug | A chemotherapy drug in the market |
| Aconiticacid | Linker | A material that exists in the human body |
| Lysine | Spacer | An essential amino acid |
| Poly(phosphazene) | Backbone | Real cases of the material used in humans(in US and Europe) |
| MPEG 550 | Solubilizing | A material used the most for drug delivery systems |
FEATURES OF POLYTAXEL
→ Due to the low toxicity and less side effects that Polytaxel presents,
the NOAEL* of the drug is significantly greater than that of other anticancer drugs.
→ Polytaxel effectively kills tumor cells when administered in doses below the NOAEL.
* NOAEL: No-Observed-Adverse-Effect Level
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A DRUG DEVELOPED TO PRESENT
THE SIGNIFICANTLY GREATER NOAEL
COMPARED WITH OTHER ANTICANCER DRUGS
comparison of actual dose vs noael
Docetaxel
Existing anticancer drugs, which create cytotoxicity,
have to be administered in doses dozens of times higher
than the NOAEL because the NOAEL is too low.
polytaxel
Polytaxel was developed to present the significantly greater
NOAEL(by up to 44 times) compared with docetaxel,
an existing broad-spectrum anticancer drug.
paradigm shift 
MOVING TO PAIN-FREE CANCER TREATMENT THROUGH THE USE OF NOAEL
→ Polytaxel, which is called a ‘pain-free anticancer drug’, is a new material developed by encapsulating docetaxel, a typical type of chemotherapy, in advanced macromolecule-based drug delivery systems.The drug, which is about 10cm,are designed to be nano-sized so thatitis effectively delivered to organs into which drugs can’t be easily carried such as the pancreas. Additionally, docetaxel has been modified to overcome poor water-solubility so that the drug can be more effectively delivered to vital organs.
